Imbalances in brain neurotransmitters such as serotonin, dopamine, and GABA contribute to symptoms of mood changes and anxiety.[1,2,3] Saffron Extract promotes serotonin and neurotransmitter balance in the brain, helping to reduce levels of anxiousness and stress response for a sense of calm.*

Supplementing with Saffron Extract supports healthy mood balance and positive outlook and provides antioxidant support for healthy inflammatory response and central (CNS) nervous system function. Adding this supplement to your daily regimen can support healthy brain function and healthy vitality in addition to helping support a healthy response to anxiousness for restful sleep. Saffron can even support a positive response to PMS symptoms.*

Vital Nutrients Saffron Extract comes in small, easy-to-take capsules using bioactive saffron components at clinically studied doses.[4,5]

It works by supporting the balance of serotonin metabolism in the microbiome, influencing tryptophan and serotonin responses in the brain, which also indirectly supports healthy dopamine and GABA expression, as well as modulation of the HPA axis, antioxidant support, and immune support.[4,6]

Packaging and label may vary.

References:
1. Pourhamzeh M. Cell Mol Neurobiol. 2022;42(6):1671-1692.
2. Grace A. Nat Rev Neurosci. 2016;17(8):524-532.
3. Conde KM. Metabolism. 2025;163:156099.
4. Lin S et al. Psychopharmacology. 2022;239:3657-3677.
5. Mena-Garcia A et al. Foods. 2023;12:1634.
6. Shafiee M. J Affect Disord. 2018;227:330-337.